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In-Vivo Imaging of Early Stages of Rheumatoid Arthritis by α5β1- Integrin Targeted Positron Emission Tomography
pH-Dependency of the Spin-Lattice Relaxation Constant (T1) of 13C-Labelled Hyperpolarized Biomolecules
Simultaneous characterization of tumor cellularity and the Warburg effect with PET, MRI and hyperpolarized 13C-MRSI
Multi-Spectral Optoacoustic Tomography (MSOT) of human breast cancer.
Cell Metabolism. Non-invasive measurement of brown fat metabolism based on optoacoustic imaging of hemoglobin gradients
Dimer formation of GdDO3A-arylsulfonamide complexes causes loss of pH-dependency of relaxivity
Imaging of Extracellular pH Using Hyperpolarized Molecules
Anticalins directed against vascular endothelial growth factor receptor 3 (VEGFR-3) with picomolar affinities show potential for medical therapy and in vivo imaging
Tumor uptake of anti‐CD20 Fabs depends on tumor perfusion
Probing lactate secretion in tumours with hyperpolarised NMR
Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA)
Anticalins directed against the fibronectin extra domain B as diagnostic tracers for glioblastomas
Optimisation of a system for the co-translational incorporation of a keto amino acid and its application to a tumour-specific Anticalin
89Zr-Labeled Versus 124I-Labeled aHER2 Fab with Optimized Plasma Half-Life for High-Contrast Tumor Imaging In Vivo
PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model
High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model
Limited-projection-angle hybrid fluorescence molecular tomography of multiple molecules
High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation
FMT-PCCT: Hybrid Fluorescence Molecular Tomography—X-Ray Phase-Contrast CT Imaging of Mouse Models
Levels of p27 sensitize to dual PI3K/mTOR inhibition
Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma
7Hsp70 serum levels in pet dogs—a potential diagnostic biomarker for spontaneous round cell tumors
Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy – potential markers for predicting breast cancer recurrence?
Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study
Hsp70 interactions with membrane lipids regulate cellular functions in health and disease
Preclinical_Evaluation_of_the_Hsp70_Peptide_Tracer_TPP-PEG24-DFO_89Zr__for_Tumor-Specific_PET_CT_Imaging
Membrane_Hsp70 A_Novel_Target_for_the_Isolation_of_Circulating_Tumor_Cells_After_Epithelial-to-Mesenchymal_Transition
Modeling and predicting tumor response in radioligand therapy
Monte Carlo Simulationen zur Bestimmung der Dosiserhöhung auf zellulärer Ebene durch tumorgerichtete Gold-Nanopartikel bei der Röntgenbestrahlung
Hyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis
Synthesis and preclinical characterization of the PSMA-targeted hybrid tracer PSMA-I&F for nuclear and fluorescence imaging of prostate cancer
The effect of total tumor volume on the biologically effective dose of tumor and kidneys for 177Lu-labelled PSMA peptides
68Ga-PSMA-HBED-CC uptake in cervical, coeliac and sacral ganglia as an important pitfall in prostate cancer PET imaging.
Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE): Proposed miTNM Classification for the Interpretation of PSMA-Ligand PET/CT
Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)
Efficacy, Predictive Factors, and Prediction Nomograms for 68Ga-labeled Prostate-specific Membrane Antigen–ligand Positron-emission Tomography/Computed Tomography in Early Biochemical Recurrent Prostate Cancer After Radical Prostatectomy
Head-to-head comparison of 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT in a case series of 10 patients with prostate cancer recurrence
Actual impact of 68Ga-PSMA-11 PET/CT on the management of prostate cancer patients with biochemical recurrence.
Animal models of MEN1
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: a novel model of invasive medullary thyroid carcinoma
68Ga-PSMA-11 PET/CT mapping of prostate cancer biochemical recurrence following radical prostatectomy in 270 patients with PSA<1.0ng/ml: Impact on Salvage Radiotherapy Planning
The role of p27 in pheochromocytoma development
Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo
Anticalins directed against vascular endothelial growth factor receptor 3 (VEGFR-3) with picomolar affinities show potential for medical therapy and in vivo imaging
Zero-valent Fe confined mesoporous silica nanocarriers (Fe(0) @ MCM-41) for targeting experimental orthotopic glioma in rats
70-kDa heat shock protein coated magnetic nanocarriers as a nanovaccine for induction of anti-tumor immune response in experimental glioma
Anticalins directed against the fibronectin extra domain B as diagnostic tracers for glioblastomas
Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas
α-Radioimmunotherapy with 213-Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma
SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary
ALDH1A1 expression increases in recurrent Glioblastoma patients and predicts a chemoresistant phenotype
Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Technical considerations on the validity of blood oxygenation level-dependent-based MR assessment of vascular deoxygenation
Hypoxia upregulates aldehyde dehydrogenase isoform 1 (ALDH1) expression and induces functional stem cell characteristics in human glioblastoma cells
Aldehyde dehydrogenase 1A1- a new mediator of resistance to temozolomide in glioblastoma
MR-based hypoxia measures in human glioma
Deficiency of caveolin-1 in APCmin/+ mice promotes colorectal tumorigenesis
Caveolin-1 Protects B6129 Mice against Helicobacter pylori Gastritis
T2* Mapping with Background Gradient Correction Using Different Excitation Pulse Shapes
Non-targeted effects of photon and particle irradiation and the interaction with the immune system.
Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors
Radiation, inflammation, and immune responses in cancer.
Bile Acids Down Regulate Caveolin-1 in Esophageal Epithelial Celis through Sterol Responsive Element-Binding Protein
Mesenchymal stem cells and glioma cells form a structural as well as a functional syncytium in vitro
Cryptate mediated nucleophilic 18F-fluorination without azeotropic drying
Basal HIF-1α expression levels are not predictive for radiosensitivity of human cancer cell lines
Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation
Chronic inflammation in cancer development
TFAP2E–DKK4 and Chemoresistance in Colorectal Cancer
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer
A novel expression and purification system for the production of enzymatic and biologically active human granzyme B
Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells
(18)F-FDG PET-guided salvage neoadjuvant radiochemotherapy of adenocarcinoma of the esophagogastric junction: the MUNICON II trial
Detection of irradiation-induced, membrane heat shock protein 70 (Hsp70) in mouse tumors using Hsp70 Fab fragment
Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody
Distinguishing integral and receptor-bound heat shock protein 70 (Hsp70) on the cell surface by Hsp70 specific antibodies
Irradiation-Induced Up-Regulation of HLA-E on Macrovascular Endothelial Cells Confers Protection against Killing by Activated Natural Killer Cells
TNF-a respecifies human mesenchymal stem cells to a neural fate and promotes migration toward experimental glioma
Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity
Classifiation of HER2/neu Status in Gastric Cancer Using a Breast-Cancer Derived Proteome Classfier
In vivo imaging of CT26 mouse tumors by using cmHsp70.1 monoclonal antibody
Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions
Gene editing enables T cell engineering to redirect antigen specificity for potent tumor rejection
Snail drives the cell cycle and determines immune cell profile in pancreatic ductal adenocarcinoma
Mesenchymal stem cell-mediated sodium iodide symporter (NIS) reporter gene delivery in an orthotopic glioblastoma mouse model
Heat-inducible mesenchymal stem cell-mediated sodium iodide symporter (NIS) gene transfer
Adaptive rewiring of oncogenic signaling in response to MTOR blockade in pancreatic cancer
T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target
Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model: MALDI imaging mass spectrometry in comparative medicine
MTOR inhibitor-based combination therapies for pancreatic cancer
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
Oncogenic signalling of cancer drivers - Context matters
Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells
Evaluierung und prognostische Bedeutung multiparametrischer Magnetresonanz-Bildgebungsmethoden im PDAC
Co-clinical assessment of tumor cellularity in pancreatic cancer
HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer
Anovel pseudotyped vesicular stomatitis virus vector for improved safety and efficacy for therapy of hepatocellular carcinoma
Determination of the detection limit of T cell receptor-transgenic effector T cells for quantification of the effective dose by PET/CT imaging
Concepts to target MYC in pancreatic cancer
Immuno-PET Imaging of Engineered Human T Cells in Tumors
Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Modeling Therapy Response and Spatial Tissue Distribution of Erlotinib in Pancreatic Cancer
New drugs for medullary thyroid cancer: new promises?
KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
PI3K signaling in pancreatic cancer progression and maintenance
Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib
STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma
Disclosing the CXCR4 Expression in Lymphoproliferative Diseases by Targeted Molecular Imaging
Direct Parametric Image Reconstruction in Reduced Parameter Space for Rapid Multi-Tracer PET Imaging
GP130 activation induces myeloma and collaborates with MYC
Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis
Biodistribution and Radiation Dosimetry for the Chemokine Receptor CXCR4-Targeting Probe 68Ga-Pentixafor
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer
PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma
MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma
Advanced radioiodine-refractory differentiated thyroid cancer: the sodium iodide symporter and other emerging therapeutic targets.
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.
Week one FLT-PET response predicts complete remission to R-CHOP and survival in DLBCL
Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells
Sorting out Pandora´s Box: discerning the dynamic roles of liver microenvironment in oncolytic virus therapy for hepatocellular carcinoma
Limited-projection-angle hybrid fluorescence molecular tomography of multiple molecules
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma
Antifibrotic Properties of Transarterial Oncolytic VSV Therapy for Hepatocellular Carcinoma in Rats with Thioacetamide-Induced Liver Fibrosis
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy
Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
Efemp1 and p27 Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models
[18F]FLT is superior to [18F]FDG for predicting early response to antiporliferative treatment in high-grade lymphoma in a dose-dependent manner
FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy
Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma
Assessing antiangiogenic therapy response by DCE-MRI: development of a physiology driven multi-compartment model using population pharmacometrics.
Free-breathing quantitative dynamic contrast-enhanced magnetic resonance imaging in a rat liver tumor model using dynamic radial T(1) mapping
In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging
Predictive value of initial 18F-FLT uptake in patients with aggressive non-Hodgkin lymphoma receiving R-CHOP treatment
Endogenous mouse models of pancreatic adenocarcinoma as a preclinical trial platform characterized by multiparametric magnetic resonance imaging
Optical imaging of integrin αVß3 detects pancreatic cancer in endogenous mouse models
Monitoring of pancreatic ductal adenocarcinoma in mouse models via multiparametric magnetic resonance imaging
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization.
Reference Region-Based Pharmacokinetic Modeling in Quantitative Dynamic Contract-Enhanced MRI Allows Robust Treatment Monitoring in a Rat Liver Tumor Model Despite Cardiovascular Changes
First demonstration of 3-D lymphatic mapping in breast cancer using freehand SPECT
Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state
Cell Cycle Progression or Translation Control Is Not Essential for Vesicular Stomatitis Virus Oncolysis of Hepatocellular Carcinoma
Antifungal Therapy with Itraconazole Impairs the Anti-Lymphoma Effects of Rituximab by Inhibiting Recruitment of CD20 to Cell Surface Lipid Rafts
Targeted Radioiodine Therapy of Neuroblastoma Tumors following Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene
PI3K Signaling Maintains c-myc Expression to Regulate Transcription of E2F1 in Pan-creatic Cancer Cells
Development of imaging strategies for investigation of TCR with defined antitumor reactivity in vivo
Classifcation of Polar Maps from Cardiac Perfusion Imaging with Graph-Convolutional Neural Networks
A novel chimeric oncolytic virus vector for improved safety and efficacy in hepatocellular carcinoma
The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity
Evaluierung und prognostische Bedeutung multiparametrischer Magnetresonanz-Bildgebungsmethoden im PDAC
Co-clinical assessment of tumor cellularity in pancreatic cancer
[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy.
Immuno-PET Imaging of Engineered Human T Cells in Tumors
Probing lactate secretion in tumours with hyperpolarised NMR
Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3
Modeling Therapy Response and Spatial Tissue Distribution of Erlotinib in Pancreatic Cancer
Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia.
Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3.
Structure-Preserving Color Normalization and Sparse Stain Separation for Histological Images.
A Continuously Infused Microfluidic Radioassay System for the Characterization of Cellular Pharmacokinetics
Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin.
High-resolution MALDI-FT-ICR MS Imaging for the analysis of metabolites from formalin-fixed paraffin-embedded clinical tissue samples
Spatially Resolved Quantification of Gadolinium(III)-Based Magnetic Resonance Agents in Tissue by MALDI Imaging Mass Spectrometry after In Vivo MRI
PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Mode
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry
Non-Negative Matrix Factorization Based Input Function Extraction for Mouse Imaging in Small Animal PET Comparison with Arterial Blood Sampling and Factor Analysis
68Ga-NODAGA-RGD is a suitable substitute for 18F-Galacto-RGD and can be produced with high specific activity in a cGMP/GRP compliant automated process
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues
Classification of HER2 Receptor Status in Breast Cancer Tissues by MALDI Imaging Mass Spectrometry




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22.05.2019 13:00
The curious case of the molecular subtypes of glioblastoma
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Girls´ Day-Angebot im TranslaTUM
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HSP110 as a therapeutic target in colorectal cancer: from crystals to drug selection
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Lecture “From yolk sac to neurodegeneration: the multiple facets if microgli” by